Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
Identifieur interne : 001038 ( Main/Exploration ); précédent : 001037; suivant : 001039Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
Auteurs : Alice Huertas [France] ; David Montani [France] ; Laurent Savale [France] ; Jérémie Pichon [France] ; Ly Tu [France] ; Florence Parent [France] ; Christophe Guignabert [France] ; Marc Humbert [France]Source :
- The European respiratory journal [ 1399-3003 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
DOI: 10.1183/13993003.01634-2020
PubMed: 32554538
PubMed Central: PMC7301835
Affiliations:
Links toward previous steps (curation, corpus...)
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Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Montani, David" sort="Montani, David" uniqKey="Montani D" first="David" last="Montani">David Montani</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Savale, Laurent" sort="Savale, Laurent" uniqKey="Savale L" first="Laurent" last="Savale">Laurent Savale</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Pichon, Jeremie" sort="Pichon, Jeremie" uniqKey="Pichon J" first="Jérémie" last="Pichon">Jérémie Pichon</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Tu, Ly" sort="Tu, Ly" uniqKey="Tu L" first="Ly" last="Tu">Ly Tu</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation></author><author><name sortKey="Parent, Florence" sort="Parent, Florence" uniqKey="Parent F" first="Florence" last="Parent">Florence Parent</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Guignabert, Christophe" sort="Guignabert, Christophe" uniqKey="Guignabert C" first="Christophe" last="Guignabert">Christophe Guignabert</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation></author><author><name sortKey="Humbert, Marc" sort="Humbert, Marc" uniqKey="Humbert M" first="Marc" last="Humbert">Marc Humbert</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32554538</idno><idno type="pmid">32554538</idno><idno type="doi">10.1183/13993003.01634-2020</idno><idno type="pmc">PMC7301835</idno><idno type="wicri:Area/Main/Corpus">000D29</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000D29</idno><idno type="wicri:Area/Main/Curation">000D29</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000D29</idno><idno type="wicri:Area/Main/Exploration">000D29</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?</title><author><name sortKey="Huertas, Alice" sort="Huertas, Alice" uniqKey="Huertas A" first="Alice" last="Huertas">Alice Huertas</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France alice.huertas@inserm.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Montani, David" sort="Montani, David" uniqKey="Montani D" first="David" last="Montani">David Montani</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Savale, Laurent" sort="Savale, Laurent" uniqKey="Savale L" first="Laurent" last="Savale">Laurent Savale</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Pichon, Jeremie" sort="Pichon, Jeremie" uniqKey="Pichon J" first="Jérémie" last="Pichon">Jérémie Pichon</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Tu, Ly" sort="Tu, Ly" uniqKey="Tu L" first="Ly" last="Tu">Ly Tu</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation></author><author><name sortKey="Parent, Florence" sort="Parent, Florence" uniqKey="Parent F" first="Florence" last="Parent">Florence Parent</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author><author><name sortKey="Guignabert, Christophe" sort="Guignabert, Christophe" uniqKey="Guignabert C" first="Christophe" last="Guignabert">Christophe Guignabert</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation></author><author><name sortKey="Humbert, Marc" sort="Humbert, Marc" uniqKey="Humbert M" first="Marc" last="Humbert">Marc Humbert</name><affiliation wicri:level="1"><nlm:affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson</wicri:regionArea><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion><wicri:noRegion>Le Plessis-Robinson</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre</wicri:regionArea><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion><wicri:noRegion>Le Kremlin-Bicêtre</wicri:noRegion></affiliation></author></analytic><series><title level="j">The European respiratory journal</title><idno type="eISSN">1399-3003</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Betacoronavirus (MeSH)</term><term>Coronavirus Infections (MeSH)</term><term>Endothelial Cells (MeSH)</term><term>Humans (MeSH)</term><term>Intensive Care Units (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (epidemiology)</term><term>Venous Thromboembolism (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Betacoronavirus (MeSH)</term><term>Cellules endothéliales (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (épidémiologie)</term><term>Thromboembolisme veineux (MeSH)</term><term>Unités de soins intensifs (MeSH)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Betacoronavirus</term><term>Coronavirus Infections</term><term>Endothelial Cells</term><term>Humans</term><term>Intensive Care Units</term><term>Pandemics</term><term>Venous Thromboembolism</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Betacoronavirus</term><term>Cellules endothéliales</term><term>Humains</term><term>Infections à coronavirus</term><term>Pandémies</term><term>Thromboembolisme veineux</term><term>Unités de soins intensifs</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Automated" Owner="NLM"><PMID Version="1">32554538</PMID><DateCompleted><Year>2020</Year><Month>08</Month><Day>04</Day></DateCompleted><DateRevised><Year>2020</Year><Month>08</Month><Day>04</Day></DateRevised><Article PubModel="Electronic-Print"><Journal><ISSN IssnType="Electronic">1399-3003</ISSN><JournalIssue CitedMedium="Internet"><Volume>56</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>07</Month></PubDate></JournalIssue><Title>The European respiratory journal</Title><ISOAbbreviation>Eur. Respir. J.</ISOAbbreviation></Journal><ArticleTitle>Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">2001634</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1183/13993003.01634-2020</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Huertas</LastName><ForeName>Alice</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0001-8545-747X</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France alice.huertas@inserm.fr.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montani</LastName><ForeName>David</ForeName><Initials>D</Initials><Identifier Source="ORCID">0000-0002-9358-6922</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Savale</LastName><ForeName>Laurent</ForeName><Initials>L</Initials><Identifier Source="ORCID">0000-0002-6862-8975</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pichon</LastName><ForeName>Jérémie</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tu</LastName><ForeName>Ly</ForeName><Initials>L</Initials><Identifier Source="ORCID">0000-0003-2336-5099</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Parent</LastName><ForeName>Florence</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guignabert</LastName><ForeName>Christophe</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0002-8545-4452</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Humbert</LastName><ForeName>Marc</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0003-0703-2892</Identifier><AffiliationInfo><Affiliation>Université Paris-Saclay, School of Medicine, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, Le Plessis-Robinson, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, Pulmonary Hypertension National Referral Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016421">Editorial</PublicationType><PublicationType UI="D016420">Comment</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur Respir J</MedlineTA><NlmUniqueID>8803460</NlmUniqueID><ISSNLinking>0903-1936</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentOn"><RefSource>Eur Respir J. 2020 Jul 30;56(1):</RefSource><PMID Version="1">32398294</PMID></CommentsCorrections><CommentsCorrections RefType="CommentOn"><RefSource>Eur Respir J. 2020 Jul 30;56(1):</RefSource><PMID Version="1">32398297</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D042783" MajorTopicYN="N">Endothelial Cells</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054556" MajorTopicYN="Y">Venous Thromboembolism</DescriptorName></MeshHeading></MeshHeadingList><CoiStatement>Conflict of interest: A. Huertas has nothing to disclose. Conflict of interest: D. Montani reports grants and personal fees from Actelion and Bayer, personal fees from GSK, Pfizer, Chiesi and Boehringer, grants, personal fees and non-financial support from MSD, non-financial support from Acceleron, outside the submitted work. Conflict of interest: L. Savale reports personal fees and non-financial support from Actelion and Bayer, grants and personal fees from GSK, outside the submitted work. Conflict of interest: J. Pichon has nothing to disclose. Conflict of interest: L. Tu has nothing to disclose. Conflict of interest: F. Parent reports grants from Bayer, CSL Behring and Sanofi, outside the submitted work. Conflict of interest: C. Guignabert has nothing to disclose. Conflict of interest: M. Humbert reports grants and personal fees from Actelion, Bayer, GSK and Acceleron, personal fees from Merck and United Therapeutics, outside the submitted work.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>06</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>6</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>6</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32554538</ArticleId><ArticleId IdType="pii">13993003.01634-2020</ArticleId><ArticleId 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